Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair

Several classes of inhibitors of the mammalian target of rapamycin (mTOR) have been developed based on its central role in sensing growth factor and nutrient levels to regulate cellular metabolism. However, its ATP-binding site closely resembles other phosphatidylinositol 3-kinase-related kinase (PI...

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Bibliographic Details
Published in:Radiat Res
Main Authors: Udayakumar, Durga, Pandita, Raj K., Horikoshi, Nobuo, Liu, Yan, Liu, Qingsong, Wong, Kwok-Kin, Hunt, Clayton R., Gray, Nathanael S., Minna, John D., Pandita, Tej K., Westover, Kenneth D.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922265/
https://ncbi.nlm.nih.gov/pubmed/27135971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14373.1
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