Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair

Several classes of inhibitors of the mammalian target of rapamycin (mTOR) have been developed based on its central role in sensing growth factor and nutrient levels to regulate cellular metabolism. However, its ATP-binding site closely resembles other phosphatidylinositol 3-kinase-related kinase (PI...

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Bibliografski detalji
Izdano u:Radiat Res
Glavni autori: Udayakumar, Durga, Pandita, Raj K., Horikoshi, Nobuo, Liu, Yan, Liu, Qingsong, Wong, Kwok-Kin, Hunt, Clayton R., Gray, Nathanael S., Minna, John D., Pandita, Tej K., Westover, Kenneth D.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922265/
https://ncbi.nlm.nih.gov/pubmed/27135971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14373.1
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