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Chromatin modifications and the DNA damage response to ionizing radiation

In order to survive, cells have evolved highly effective repair mechanisms to deal with the potentially lethal DNA damage produced by exposure to endogenous as well as exogenous agents. Ionizing radiation exposure induces highly lethal DNA damage, especially DNA double-strand breaks (DSBs), that is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kumar, Rakesh, Horikoshi, Nobuo, Singh, Mayank, Gupta, Arun, Misra, Hari S., Albuquerque, Kevin, Hunt, Clayton R., Pandita, Tej K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551241/
https://ncbi.nlm.nih.gov/pubmed/23346550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00214
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