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Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
New structures of RNA polymerase II (pol II) transcribing complexes reveal a likely key to transcription. The trigger loop swings beneath a correct nucleoside triphosphate (NTP) in the nucleotide addition site, closing off the active center, and forming an extensive network of interactions with the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876690/ https://ncbi.nlm.nih.gov/pubmed/17129781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.11.023 |
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