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The RNA Polymerase II Trigger Loop Functions in Substrate Selection and is Directly Targeted by α-amanitin

Structural, biochemical and genetic studies have led to proposals that a mobile element of multi-subunit RNA polymerases, the Trigger Loop (TL), plays a critical role in catalysis and can be targeted by antibiotic inhibitors. Here we present evidence that the Saccharomyces cerevisiae RNA Polymerase...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kaplan, Craig D., Larsson, Karl-Magnus, Kornberg, Roger D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475549/
https://ncbi.nlm.nih.gov/pubmed/18538653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.04.023
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