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Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II

During transcription, RNA polymerase II (RNAPII) must select the correct nucleotide, catalyze its addition to the growing RNA transcript, and move stepwise along the DNA until a gene is fully transcribed. In all kingdoms of life, transcription must be finely tuned to ensure an appropriate balance be...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Larson, Matthew H., Zhou, Jing, Kaplan, Craig D., Palangat, Murali, Kornberg, Roger D., Landick, Robert, Block, Steven M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340090/
https://ncbi.nlm.nih.gov/pubmed/22493230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200939109
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