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Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II
During transcription, RNA polymerase II (RNAPII) must select the correct nucleotide, catalyze its addition to the growing RNA transcript, and move stepwise along the DNA until a gene is fully transcribed. In all kingdoms of life, transcription must be finely tuned to ensure an appropriate balance be...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340090/ https://ncbi.nlm.nih.gov/pubmed/22493230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200939109 |
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