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Structural basis of transcription: α-Amanitin–RNA polymerase II cocrystal at 2.8 Å resolution
The structure of RNA polymerase II in a complex with the inhibitor α-amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122170/ https://ncbi.nlm.nih.gov/pubmed/11805306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251664698 |
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