Structural basis of transcription: α-Amanitin–RNA polymerase II cocrystal at 2.8 Å resolution
The structure of RNA polymerase II in a complex with the inhibitor α-amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122170/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805306/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251664698 |
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