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Structural basis of transcription: α-Amanitin–RNA polymerase II cocrystal at 2.8 Å resolution

The structure of RNA polymerase II in a complex with the inhibitor α-amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Bushnell, David A., Cramer, Patrick, Kornberg, Roger D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122170/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805306/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251664698
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