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RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
A structurally conserved element, the trigger loop, has been suggested to play a key role in substrate selection and catalysis of RNA polymerase II (pol II) transcription elongation. Recently resolved X-ray structures showed that the trigger loop forms direct interactions with the β-phosphate and ba...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936645/ https://ncbi.nlm.nih.gov/pubmed/20798057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009898107 |
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