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RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription

A structurally conserved element, the trigger loop, has been suggested to play a key role in substrate selection and catalysis of RNA polymerase II (pol II) transcription elongation. Recently resolved X-ray structures showed that the trigger loop forms direct interactions with the β-phosphate and ba...

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Detalhes bibliográficos
Main Authors: Huang, Xuhui, Wang, Dong, Weiss, Dahlia R., Bushnell, David A., Kornberg, Roger D., Levitt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936645/
https://ncbi.nlm.nih.gov/pubmed/20798057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009898107
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