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Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center
Nucleoside triphosphates (NTPs) diffuse to the active center of RNA polymerase II through a funnel-shaped opening that narrows to a negatively charged pore. Computer simulation shows that the funnel and pore reduce the rate of diffusion by a factor of ≈2 × 10(–7). The resulting limitation on the rat...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC536049/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15574497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408168101 |
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