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Templated nucleoside triphosphate binding to a noncatalytic site on RNA polymerase regulates transcription
The regulation of RNA synthesis by RNA polymerase (RNAP) is essential for proper gene expression. Crystal structures of RNAP reveal two channels: the main channel that contains the downstream DNA and a secondary channel that leads directly to the catalytic site. Although nucleoside triphosphates (NT...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076813/ https://ncbi.nlm.nih.gov/pubmed/21447716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011274108 |
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