Templated nucleoside triphosphate binding to a noncatalytic site on RNA polymerase regulates transcription

Por Kennedy, Scott R., Erie, Dorothy A.
Publicado em 2011

Forks, Pincers, and Triggers: The Tools for Nucleotide Incorporation and Translocation in Multi-subunit RNA Polymerases

Por Erie, Dorothy A., Kennedy, Scott R.
Publicado em 2009

Somatic Mutations in Aging, Cancer and Neurodegeneration

Por Kennedy, Scott R., Loeb, Lawrence A., Herr, Alan J.
Publicado em 2011

Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage

Por Kennedy, Scott R., Salk, Jesse J., Schmitt, Michael W., Loeb, Lawrence A.
Publicado em 2013

Mitochondrial DNA Mutations Increase in Early Stage Alzheimer’s Disease and are Inconsistent with Oxidative Damage

Por Hoekstra, Jake G., Hipp, Michael J., Montine, Thomas J., Kennedy, Scott R.
Publicado no Ann Neurol (2016)

The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the Malaria parasite Plasmodium falciparum

Por Kennedy, Scott R., Chen, Cheng-Yao, Schmitt, Michael W., Bower, Cole N., Loeb, Lawrence A.
Publicado em 2011

DNA Replication Error-Induced Extinction of Diploid Yeast

Por Herr, Alan J., Kennedy, Scott R., Knowels, Gary M., Schultz, Eric M., Preston, Bradley D.
Publicado em 2014

Volatility of Mutator Phenotypes at Single Cell Resolution

Por Kennedy, Scott R., Schultz, Eric M., Chappell, Thomas M., Kohrn, Brendan, Knowels, Gary M., Herr, Alan J.
Publicado no PLoS Genet (2015)

Normally lethal amino acid substitutions suppress an ultramutator DNA Polymerase δ variant

Por Dennis, Daniel G., McKay-Fleisch, Jill, Eitzen, Kaila, Dowsett, Ian, Kennedy, Scott R., Herr, Alan J.
Publicado no Sci Rep (2017)

Detection of ultra-rare mutations by next-generation sequencing

Por Schmitt, Michael W., Kennedy, Scott R., Salk, Jesse J., Fox, Edward J., Hiatt, Joseph B., Loeb, Lawrence A.
Publicado em 2012

Oxidative Stress Is Not a Major Contributor to Somatic Mitochondrial DNA Mutations

Por Itsara, Leslie S., Kennedy, Scott R., Fox, Edward J., Yu, Selina, Hewitt, Joshua J., Sanchez-Contreras, Monica, Cardozo-Pelaez, Fernando, Pallanck, Leo J.
Publicado em 2014

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

Por Pickrell, Alicia M., Huang, Chiu-Hui, Kennedy, Scott R., Ordureau, Alban, Sideris, Dionisia P., Hoekstra, Jake G., Harper, J. Wade, Youle, Richard J.
Publicado no Neuron (2015)

Werner syndrome through the lens of tissue and tumour genomics

Por Tokita, Mari, Kennedy, Scott R., Risques, Rosa Ana, Chun, Stephen G., Pritchard, Colin, Oshima, Junko, Liu, Yan, Bryant-Greenwood, Peter K., Welcsh, Piri, Monnat, Raymond J.
Publicado no Sci Rep (2016)

Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues

Por Krimmel, Jeffrey D., Schmitt, Michael W., Harrell, Maria I., Agnew, Kathy J., Kennedy, Scott R., Emond, Mary J., Loeb, Lawrence A., Swisher, Elizabeth M., Risques, Rosa Ana
Publicado no Proc Natl Acad Sci U S A (2016)

A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

Por Patel, Maulik R, Miriyala, Ganesh K, Littleton, Aimee J, Yang, Heiko, Trinh, Kien, Young, Janet M, Kennedy, Scott R, Yamashita, Yukiko M, Pallanck, Leo J, Malik, Harmit S
Publicado no eLife (2016)

Detecting ultralow-frequency mutations by Duplex Sequencing

Por Kennedy, Scott R, Schmitt, Michael W, Fox, Edward J, Kohrn, Brendan F, Salk, Jesse J, Ahn, Eun Hyun, Prindle, Marc J, Kuong, Kawai J, Shen, Jiang-Cheng, Risques, Rosa-Ana, Loeb, Lawrence A
Publicado no Nat Protoc (2014)