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Detecting ultralow-frequency mutations by Duplex Sequencing
Duplex Sequencing (DS) is a next-generation sequencing methodology capable of detecting a single mutation among >1 × 10(7) wild-type nucleotides, thereby enabling the study of heterogeneous populations and very-low-frequency genetic alterations. DS can be applied to any double-stranded DNA sample...
Tallennettuna:
| Julkaisussa: | Nat Protoc |
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| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271547/ https://ncbi.nlm.nih.gov/pubmed/25299156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.170 |
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