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Mutational Heterogeneity in Human Cancers: Origin and Consequences
Cancer recapitulates Darwinian evolution. Mutations acquired during life that provide cells with a growth or survival advantage will preferentially multiply to form a tumor. As a result of The Cancer Genome Atlas project we have now gathered detailed information on the nucleotide sequence changes in...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375045/ https://ncbi.nlm.nih.gov/pubmed/19743960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-121808-102113 |
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