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Human cancers express mutator phenotypes: origin, consequences and targeting

Recent data on DNA sequencing of human tumours have established that cancer cells contain thousands of mutations. These data support the concept that cancer cells express a mutator phenotype. This Perspective considers the evidence supporting the mutator phenotype hypothesis, the origin and conseque...

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Kaydedildi:
Detaylı Bibliyografya
Yazar: Loeb, Lawrence A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007007/
https://ncbi.nlm.nih.gov/pubmed/21593786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3063
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