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Human cancers express a mutator phenotype
Cancer cells contain numerous clonal mutations, i.e., mutations that are present in most or all malignant cells of a tumor and have presumably been selected because they confer a proliferative advantage. An important question is whether cancer cells also contain a large number of random mutations, i...
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Autori principali: | , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
National Academy of Sciences
2006
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636340/ https://ncbi.nlm.nih.gov/pubmed/17108085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607057103 |
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