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Human cancers express a mutator phenotype

Cancer cells contain numerous clonal mutations, i.e., mutations that are present in most or all malignant cells of a tumor and have presumably been selected because they confer a proliferative advantage. An important question is whether cancer cells also contain a large number of random mutations, i...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Bielas, Jason H., Loeb, Keith R., Rubin, Brian P., True, Lawrence D., Loeb, Lawrence A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636340/
https://ncbi.nlm.nih.gov/pubmed/17108085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607057103
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