Proliferation is necessary for both repair and mutation in transgenic mouse cells

по Bielas, Jason H., Heddle, John A.
Опубликовано 2000

Elevated mutagenesis and decreased DNA repair at a transgene are associated with proliferation but not apoptosis in p53-deficient cells

по Bielas, Jason H., Heddle, John A.
Опубликовано 2003

Quantification of random mutations in the mitochondrial genome

по Vermulst, Marc, Bielas, Jason H., Loeb, Lawrence A.
Опубликовано 2008

Response to: ‘when man got his mtDNA deletions?’

по Taylor, Sean D, Salk, Jesse J, Bielas, Jason H
Опубликовано в: Aging Cell (2014)

Molecularly Evolved Thymidylate Synthase Inhibits 5-Fluorodeoxyuridine Toxicity in Human Hematopoietic Cells

по Bielas, Jason H., Schmitt, Michael W., Icreverzi, Amalia, Ericson, Nolan G., Loeb, Lawrence A.
Опубликовано 2009

Human cancers express a mutator phenotype

по Bielas, Jason H., Loeb, Keith R., Rubin, Brian P., True, Lawrence D., Loeb, Lawrence A.
Опубликовано 2006

Mitochondrial DNA exhibits resistance to induced point and deletion mutations

по Valente, William J., Ericson, Nolan G., Long, Alexandra S., White, Paul A., Marchetti, Francesco, Bielas, Jason H.
Опубликовано в: Nucleic Acids Res (2016)

Simultaneous digital quantification and fluorescence-based size characterization of massively parallel sequencing libraries

по Laurie, Matthew T., Bertout, Jessica A., Taylor, Sean D., Burton, Joshua N., Shendure, Jay A., Bielas, Jason H.
Опубликовано 2013

Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression

по Nivison, Mary P., Ericson, Nolan G., Green, Virginia M., Bielas, Jason H., Campbell, Jean S., Horner, Philip J.
Опубликовано в: Exp Neurol (2017)

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

по Ericson, Nolan G., Kulawiec, Mariola, Vermulst, Marc, Sheahan, Kieran, O'Sullivan, Jacintha, Salk, Jesse J., Bielas, Jason H.
Опубликовано 2012

A random mutation capture assay to detect genomic point mutations in mouse tissue

по Wright, Jocelyn H., Modjeski, Kristina L., Bielas, Jason H., Preston, Bradley D., Fausto, Nelson, Loeb, Lawrence A., Campbell, Jean S.
Опубликовано 2011

Digital Quantification of Tumor Infiltrating Lymphocytes

по Robins, Harlan S., Ericson, Nolan G., Guenthoer, Jamie, O'Briant, Kathy C., Tewari, Muneesh, W.Drescher, Charles, Bielas, Jason H.
Опубликовано 2013

Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects

по Crouch, Marie-Laure, Knowels, Gary, Stuppard, Rudolph, Ericson, Nolan G., Bielas, Jason H., Marcinek, David J., Syrjala, Karen L.
Опубликовано в: PLoS One (2017)

Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain

по Taylor, Sean D, Ericson, Nolan G, Burton, Joshua N, Prolla, Tomas A, Silber, John R, Shendure, Jay, Bielas, Jason H
Опубликовано 2014

Targeted single molecule mutation detection with massively parallel sequencing

по Gregory, Mark T., Bertout, Jessica A., Ericson, Nolan G., Taylor, Sean D., Mukherjee, Rithun, Robins, Harlan S., Drescher, Charles W., Bielas, Jason H.
Опубликовано в: Nucleic Acids Res (2016)

Aging Neural Progenitor Cells Have Decreased Mitochondrial Content and Lower Oxidative Metabolism

по Stoll, Elizabeth A., Cheung, Willy, Mikheev, Andrei M., Sweet, Ian R., Bielas, Jason H., Zhang, Jing, Rostomily, Robert C., Horner, Philip J.
Опубликовано 2011

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

по Hu, Jie, Locasale, Jason W., Bielas, Jason H., O’Sullivan, Jacintha, Sheahan, Kieran, Cantley, Lewis C., Vander Heiden, Matthew G., Vitkup, Dennis
Опубликовано 2013

Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics

по Rose, John C., Stephany, Jason J., Valente, William J., Trevillian, Bridget M., Dang, Ha V., Bielas, Jason H., Maly, Dustin J., Fowler, Douglas M.
Опубликовано в: Nat Methods (2017)

High-throughput sequencing of T cell receptors reveals a homogeneous repertoire of tumor-infiltrating lymphocytes in ovarian cancer

по Emerson, Ryan O., Sherwood, Anna M., Rieder, Mark J., Guenthoer, Jamie, Williamson, David W., Carlson, Christopher S., Drescher, Charles W., Tewari, Muneesh, Bielas, Jason H., Robins, Harlan S.
Опубликовано в: J Pathol (2013)

Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

по Haroon, Suraiya, Li, Annie, Weinert, Jaye L., Fritsch, Clark, Ericson, Nolan G., Alexander-Floyd, Jasmine, Braeckman, Bart P., Haynes, Cole M., Bielas, Jason H., Gidalevitz, Tali, Vermulst, Marc
Опубликовано в: Cell Rep (2018)