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Aging Neural Progenitor Cells Have Decreased Mitochondrial Content and Lower Oxidative Metabolism

Although neurogenesis occurs in discrete areas of the adult mammalian brain, neural progenitor cells (NPCs) produce fewer new neurons with age. To characterize the molecular changes that occur during aging, we performed a proteomic comparison between primary-cultured NPCs from the young adult and ag...

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Bibliografski detalji
Glavni autori: Stoll, Elizabeth A., Cheung, Willy, Mikheev, Andrei M., Sweet, Ian R., Bielas, Jason H., Zhang, Jing, Rostomily, Robert C., Horner, Philip J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207440/
https://ncbi.nlm.nih.gov/pubmed/21900249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252171
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