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Aging Neural Progenitor Cells Have Decreased Mitochondrial Content and Lower Oxidative Metabolism
Although neurogenesis occurs in discrete areas of the adult mammalian brain, neural progenitor cells (NPCs) produce fewer new neurons with age. To characterize the molecular changes that occur during aging, we performed a proteomic comparison between primary-cultured NPCs from the young adult and ag...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207440/ https://ncbi.nlm.nih.gov/pubmed/21900249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252171 |
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