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A syngeneic glioma model to assess the impact of neural progenitor target cell age on tumor malignancy
Human glioma incidence, malignancy and treatment resistance are directly proportional to patient age. Cell intrinsic factors are reported to contribute to human age-dependent glioma malignancy but suitable animal models to examine the role of aging are lacking. Here we developed an orthotopic syngen...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878969/ https://ncbi.nlm.nih.gov/pubmed/19489742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00494.x |
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