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Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer
Genome instability is regarded as a hallmark of cancer. Human tumors frequently carry clonally expanded mutations in their mitochondrial DNA (mtDNA), some of which may drive cancer progression and metastasis. The high prevalence of clonal mutations in tumor mtDNA has commonly led to the assumption t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369930/ https://ncbi.nlm.nih.gov/pubmed/22685414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002689 |
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