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Skeletal muscle mitochondrial DNA deletions are not increased in CuZn-superoxide dismutase deficient mice

Mitochondrial DNA (mtDNA) deletion mutations are proposed contributors to aging-related muscle fiber loss and atrophy, but evidence of a causal role for these mutations in muscle aging is lacking. Elucidating the etiology of in vivo mtDNA deletion mutations will help to better understand and test th...

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Bibliografski detalji
Izdano u:Exp Gerontol
Glavni autori: Wanagat, Jonathan, Ahmadieh, Nazanin, Bielas, Jason, Ericson, Nolan G., Van Remmen, Holly
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289650/
https://ncbi.nlm.nih.gov/pubmed/25449857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.11.012
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