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Mitochondrial DNA exhibits resistance to induced point and deletion mutations

The accumulation of somatic mitochondrial DNA (mtDNA) mutations contributes to the pathogenesis of human disease. Currently, mitochondrial mutations are largely considered results of inaccurate processing of its heavily damaged genome. However, mainly from a lack of methods to monitor mtDNA mutation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Valente, William J., Ericson, Nolan G., Long, Alexandra S., White, Paul A., Marchetti, Francesco, Bielas, Jason H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062989/
https://ncbi.nlm.nih.gov/pubmed/27550180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw716
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