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Mitochondrial DNA exhibits resistance to induced point and deletion mutations

The accumulation of somatic mitochondrial DNA (mtDNA) mutations contributes to the pathogenesis of human disease. Currently, mitochondrial mutations are largely considered results of inaccurate processing of its heavily damaged genome. However, mainly from a lack of methods to monitor mtDNA mutation...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Valente, William J., Ericson, Nolan G., Long, Alexandra S., White, Paul A., Marchetti, Francesco, Bielas, Jason H.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062989/
https://ncbi.nlm.nih.gov/pubmed/27550180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw716
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