The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations

Studies of single cells have previously shown intracellular clonal expansion of mitochondrial DNA (mtDNA) mutations to levels that can cause a focal cytochrome c oxidase (COX) defect. Whilst techniques are available to study mtDNA rearrangements at the level of the single cell, recent interest has f...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Taylor, Robert W., Taylor, Geoffrey A., Durham, Steve E., Turnbull, Douglass M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	NAR Methods Online
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55839/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11470889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.15.e74
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