Mitochondrial mutational spectra in human cells and tissues

We have found that human organs such as colon, lung, and muscle, as well as their derived tumors, share nearly all mitochondrial hotspot point mutations. Seventeen hotspots, primarily G → A and A → G transitions, have been identified in the mitochondrial sequence of base pairs 10,030–10,130. Mutant...

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Detaylı Bibliyografya
Asıl Yazarlar: Khrapko, Konstantin, Coller, Hilary A., André, Paulo C., Li, Xiao-Cheng, Hanekamp, John S., Thilly, William G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC28387/
https://ncbi.nlm.nih.gov/pubmed/9391107
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