Mitochondrial mutational spectra in human cells and tissues

We have found that human organs such as colon, lung, and muscle, as well as their derived tumors, share nearly all mitochondrial hotspot point mutations. Seventeen hotspots, primarily G → A and A → G transitions, have been identified in the mitochondrial sequence of base pairs 10,030–10,130. Mutant...

Descripción completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Khrapko, Konstantin, Coller, Hilary A., André, Paulo C., Li, Xiao-Cheng, Hanekamp, John S., Thilly, William G.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1997
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28387/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.13798
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!