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The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations

Studies of single cells have previously shown intracellular clonal expansion of mitochondrial DNA (mtDNA) mutations to levels that can cause a focal cytochrome c oxidase (COX) defect. Whilst techniques are available to study mtDNA rearrangements at the level of the single cell, recent interest has f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Taylor, Robert W., Taylor, Geoffrey A., Durham, Steve E., Turnbull, Douglass M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55839/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11470889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.15.e74
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