Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

Genetic instability of the mitochondrial genome (mtDNA) plays an important role in human aging and disease. Thus far, it has proven difficult to develop successful treatment strategies for diseases that are caused by mtDNA instability. To address this issue, we developed a model of mtDNA disease in...

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Vydáno v:Cell Rep
Hlavní autoři: Haroon, Suraiya, Li, Annie, Weinert, Jaye L., Fritsch, Clark, Ericson, Nolan G., Alexander-Floyd, Jasmine, Braeckman, Bart P., Haynes, Cole M., Bielas, Jason H., Gidalevitz, Tali, Vermulst, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106782/
https://ncbi.nlm.nih.gov/pubmed/29562168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.099
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