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Proliferation is necessary for both repair and mutation in transgenic mouse cells

Proliferating cells are often presumed to be more mutable than quiescent cells because they have less time to repair DNA damage before DNA replication. Direct tests of this hypothesis have been confounded by the need for cell division before a mutation can be detected. We have avoided this problem b...

詳細記述

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書誌詳細
主要な著者: Bielas, Jason H., Heddle, John A.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC17210/
https://ncbi.nlm.nih.gov/pubmed/11005832
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