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Human cancers express mutator phenotypes: origin, consequences and targeting
Recent data on DNA sequencing of human tumours have established that cancer cells contain thousands of mutations. These data support the concept that cancer cells express a mutator phenotype. This Perspective considers the evidence supporting the mutator phenotype hypothesis, the origin and conseque...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007007/ https://ncbi.nlm.nih.gov/pubmed/21593786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3063 |
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