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Volatility of Mutator Phenotypes at Single Cell Resolution
Mutator phenotypes accelerate the evolutionary process of neoplastic transformation. Historically, the measurement of mutation rates has relied on scoring the occurrence of rare mutations in target genes in large populations of cells. Averaging mutation rates over large cell populations assumes that...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395103/ https://ncbi.nlm.nih.gov/pubmed/25868109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005151 |
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