Lineage Tracking for Probing Heritable Phenotypes at Single-Cell Resolution

Determining the phenotype and genotype of single cells is central to understand microbial evolution. DNA sequencing technologies allow the detection of mutants at high resolution, but similar approaches for phenotypic analyses are still lacking. We show that a drop-based millifluidic system enables...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cottinet, Denis, Condamine, Florence, Bremond, Nicolas, Griffiths, Andrew D., Rainey, Paul B., de Visser, J. Arjan G. M., Baudry, Jean, Bibette, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831777/
https://ncbi.nlm.nih.gov/pubmed/27077662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152395
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