O6-benzylguanine enhances the sensitivity of a glioma xenograft with low O6-alkylguanine-DNA alkyltransferase activity to temozolomide and BCNU.

od Wedge, S. R., Newlands, E. S.
Wydane 1996

ZD6474 – a novel inhibitor of VEGFR and EGFR tyrosine kinase activity

od Ryan, A J, Wedge, S R
Wydane 2005

Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous adm...

od Wedge, S. R., Duncan, R., Kopeckova, P.
Wydane 1991

3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltr...

od Wedge, S. R., Porteous, J. K., Newlands, E. S.
Wydane 1996

Ex vivo treatment of patient biopsies as a novel method to assess colorectal tumour response to the MEK1/2 inhibitor, Selumetinib

od Novo, Sonia M., Wedge, Stephen R., Stark, Lesley A.
Wydane w Sci Rep (2017)

Potentiation of temozolomide and BCNU cytotoxicity by O(6)-benzylguanine: a comparative study in vitro.

od Wedge, S. R., Porteus, J. K., May, B. L., Newlands, E. S.
Wydane 1996

DNAPK Inhibition Preferentially Compromises the Repair of Radiation-induced DNA Double-strand Breaks in Chronically Hypoxic Tumor Cells in Xenograft Models

od Jiang, Yanyan, Willmore, Elaine, Wedge, Stephen R., Ryan, Anderson J.
Wydane w Mol Cancer Ther (2021)

ZD1839 (‘Iressa’), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model

od Williams, K J, Telfer, B A, Stratford, I J, Wedge, S R
Wydane 2002

Use of dynamic contrast-enhanced MRI to evaluate acute treatment with ZD6474, a VEGF signalling inhibitor, in PC-3 prostate tumours

od Checkley, D, Tessier, J J, Kendrew, J, Waterton, J C, Wedge, S R
Wydane 2003

Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer

od Jones, Dominic, Noble, Martin, Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Wydane w Sci Rep (2017)

N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice.

od Seymour, L. W., Ulbrich, K., Wedge, S. R., Hume, I. C., Strohalm, J., Duncan, R.
Wydane 1991

Development of a fluorescence-based cellular apoptosis reporter

od Balderstone, Lucy A, Dawson, John C, Welman, Arkadiusz, Serrels, Alan, Wedge, Stephen R, Brunton, Valerie G
Wydane w Methods Appl Fluoresc (2019)

Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation

od Lochhead, Pamela A., Clark, Jonathan, Wang, Lan-Zhen, Gilmour, Lesley, Squires, Matthew, Gilley, Rebecca, Foxton, Caroline, Newell, David R., Wedge, Stephen R., Cook, Simon J.
Wydane w Cell Cycle (2016)

Inhibition of poly(ADP-ribose) polymerase-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft

od Senra, Joana M., Telfer, Brian A., Cherry, Kim E., McCrudden, Cian M., Hirst, David G., O’Connor, Mark J., Wedge, Stephen R., Stratford, Ian J.
Wydane 2011

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy

od O'Neill, Daniel, Jones, Dominic, Wade, Mark, Grey, James, Nakjang, Sirintra, Guo, Wenrui, Cork, David, Davies, Barry R., Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Wydane w Oncotarget (2015)

Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System

od Hallett, Stephen T., Pastok, Martyna W., Morgan, R. Marc L., Wittner, Anita, Blundell, Katie L.I.M., Felletar, Ildiko, Wedge, Stephen R., Prodromou, Chrisostomos, Noble, Martin E.M., Pearl, Laurence H., Endicott, Jane A.
Wydane w Cell Rep (2017)

O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma.

od Middleton, M. R., Lunn, J. M., Morris, C., Rustin, G., Wedge, S. R., Brampton, M. H., Lind, M. J., Lee, S. M., Newell, D. R., Bleehen, N. M., Newlands, E. S., Calvert, A. H., Margison, G. P., Thatcher, N.
Wydane 1998

Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach

od Miller, Duncan C., Martin, Mathew P., Adhikari, Santosh, Brennan, Alfie, Endicott, Jane A., Golding, Bernard T., Hardcastle, Ian R., Heptinstall, Amy, Hobson, Stephen, Jennings, Claire, Molyneux, Lauren, Ng, Yvonne, Wedge, Stephen R., Noble, Martin E. M., Cano, Celine
Wydane w Org Biomol Chem (2018)

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

od Noble, Richard A., Bell, Natalie, Blair, Helen, Sikka, Arti, Thomas, Huw, Phillips, Nicole, Nakjang, Sirintra, Miwa, Satomi, Crossland, Rachel, Rand, Vikki, Televantou, Despina, Long, Anna, Keun, Hector C., Bacon, Chris M., Bomken, Simon, Critchlow, Susan E., Wedge, Stephen R.
Wydane w Haematologica (2017)

Guidelines for the welfare and use of animals in cancer research

od Workman, P, Aboagye, E O, Balkwill, F, Balmain, A, Bruder, G, Chaplin, D J, Double, J A, Everitt, J, Farningham, D A H, Glennie, M J, Kelland, L R, Robinson, V, Stratford, I J, Tozer, G M, Watson, S, Wedge, S R, Eccles, S A
Wydane 2010