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ZD6474 – a novel inhibitor of VEGFR and EGFR tyrosine kinase activity

Angiogenesis is crucial for maintaining the supply of oxygen and nutrients required to support solid tumour growth. Inhibitors of tumour blood vessel formation are therefore being sought, in particular, inhibitors of vascular endothelial growth factor-A (VEGF)-signalling, which has a pivotal role in...

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Bibliografiske detaljer
Main Authors: Ryan, A J, Wedge, S R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362058/
https://ncbi.nlm.nih.gov/pubmed/15928657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602603
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