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ZD6474 – a novel inhibitor of VEGFR and EGFR tyrosine kinase activity

Angiogenesis is crucial for maintaining the supply of oxygen and nutrients required to support solid tumour growth. Inhibitors of tumour blood vessel formation are therefore being sought, in particular, inhibitors of vascular endothelial growth factor-A (VEGF)-signalling, which has a pivotal role in...

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Autors principals: Ryan, A J, Wedge, S R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362058/
https://ncbi.nlm.nih.gov/pubmed/15928657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602603
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