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ZD6474 – a novel inhibitor of VEGFR and EGFR tyrosine kinase activity

Angiogenesis is crucial for maintaining the supply of oxygen and nutrients required to support solid tumour growth. Inhibitors of tumour blood vessel formation are therefore being sought, in particular, inhibitors of vascular endothelial growth factor-A (VEGF)-signalling, which has a pivotal role in...

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Détails bibliographiques
Auteurs principaux: Ryan, A J, Wedge, S R
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362058/
https://ncbi.nlm.nih.gov/pubmed/15928657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602603
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