The tyrosine kinase inhibitor ZD6474 inhibits tumour growth in an intracerebral rat glioma model

Malignant glioma is characterised by extensive neovascularisation, principally influenced by vascular endothelial growth factor (VEGF). ZD6474 is a potent inhibitor of VEGF-R2 tyrosine kinase activity, but with additional inhibitory effects on other growth factors. In this study, we have investigate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sandström, M, Johansson, M, Andersson, U, Bergh, A, Bergenheim, A T, Henriksson, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2004
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747688/
https://ncbi.nlm.nih.gov/pubmed/15305185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602108
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