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The tyrosine kinase inhibitor ZD6474 inhibits tumour growth in an intracerebral rat glioma model

Malignant glioma is characterised by extensive neovascularisation, principally influenced by vascular endothelial growth factor (VEGF). ZD6474 is a potent inhibitor of VEGF-R2 tyrosine kinase activity, but with additional inhibitory effects on other growth factors. In this study, we have investigate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sandström, M, Johansson, M, Andersson, U, Bergh, A, Bergenheim, A T, Henriksson, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747688/
https://ncbi.nlm.nih.gov/pubmed/15305185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602108
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