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The tyrosine kinase inhibitor ZD6474 inhibits tumour growth in an intracerebral rat glioma model
Malignant glioma is characterised by extensive neovascularisation, principally influenced by vascular endothelial growth factor (VEGF). ZD6474 is a potent inhibitor of VEGF-R2 tyrosine kinase activity, but with additional inhibitory effects on other growth factors. In this study, we have investigate...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747688/ https://ncbi.nlm.nih.gov/pubmed/15305185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602108 |
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