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Targeting the EGF receptor in ovarian cancer with the tyrosine kinase inhibitor ZD 1839 (‘Iressa’)

The modulating effects of the orally active epidermal growth factor receptor-specific tyrosine kinase inhibitor ZD 1839 (‘Iressa’) on cell growth and signalling were evaluated in four ovarian cancer cell lines (PE01, PE04, SKOV-3, OVCAR-5) that express the epidermal growth factor receptor, and in A2...

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Detalhes bibliográficos
Main Authors: Sewell, J M, Macleod, K G, Ritchie, A, Smyth, J F, Langdon, S P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375224/
https://ncbi.nlm.nih.gov/pubmed/11875715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600058
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