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Development of a fluorescence-based cellular apoptosis reporter

Evasion of apoptosis is a hallmark of human cancer, and a desired endpoint of many anticancer agents is the induction of cell death. With the heterogeneity of cancer becoming increasingly apparent, to understand drug mechanisms of action and identify combination therapies in cell populations, the de...

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Опубликовано в: :Methods Appl Fluoresc
Главные авторы: Balderstone, Lucy A, Dawson, John C, Welman, Arkadiusz, Serrels, Alan, Wedge, Stephen R, Brunton, Valerie G
Формат: Artigo
Язык:Inglês
Опубликовано: IOP Publishing 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372133/
https://ncbi.nlm.nih.gov/pubmed/30353887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2050-6120/aae6f8
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