O6-benzylguanine enhances the sensitivity of a glioma xenograft with low O6-alkylguanine-DNA alkyltransferase activity to temozolomide and BCNU.

द्वारा Wedge, S. R., Newlands, E. S.
प्रकाशित 1996

ZD6474 – a novel inhibitor of VEGFR and EGFR tyrosine kinase activity

द्वारा Ryan, A J, Wedge, S R
प्रकाशित 2005

Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous adm...

द्वारा Wedge, S. R., Duncan, R., Kopeckova, P.
प्रकाशित 1991

3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltr...

द्वारा Wedge, S. R., Porteous, J. K., Newlands, E. S.
प्रकाशित 1996

Ex vivo treatment of patient biopsies as a novel method to assess colorectal tumour response to the MEK1/2 inhibitor, Selumetinib

द्वारा Novo, Sonia M., Wedge, Stephen R., Stark, Lesley A.
में प्रकाशित Sci Rep (2017)

Potentiation of temozolomide and BCNU cytotoxicity by O(6)-benzylguanine: a comparative study in vitro.

द्वारा Wedge, S. R., Porteus, J. K., May, B. L., Newlands, E. S.
प्रकाशित 1996

DNAPK Inhibition Preferentially Compromises the Repair of Radiation-induced DNA Double-strand Breaks in Chronically Hypoxic Tumor Cells in Xenograft Models

द्वारा Jiang, Yanyan, Willmore, Elaine, Wedge, Stephen R., Ryan, Anderson J.
में प्रकाशित Mol Cancer Ther (2021)

ZD1839 (‘Iressa’), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model

द्वारा Williams, K J, Telfer, B A, Stratford, I J, Wedge, S R
प्रकाशित 2002

Use of dynamic contrast-enhanced MRI to evaluate acute treatment with ZD6474, a VEGF signalling inhibitor, in PC-3 prostate tumours

द्वारा Checkley, D, Tessier, J J, Kendrew, J, Waterton, J C, Wedge, S R
प्रकाशित 2003

Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer

द्वारा Jones, Dominic, Noble, Martin, Wedge, Steve R., Robson, Craig N., Gaughan, Luke
में प्रकाशित Sci Rep (2017)

N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice.

द्वारा Seymour, L. W., Ulbrich, K., Wedge, S. R., Hume, I. C., Strohalm, J., Duncan, R.
प्रकाशित 1991

Development of a fluorescence-based cellular apoptosis reporter

द्वारा Balderstone, Lucy A, Dawson, John C, Welman, Arkadiusz, Serrels, Alan, Wedge, Stephen R, Brunton, Valerie G
में प्रकाशित Methods Appl Fluoresc (2019)

Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation

द्वारा Lochhead, Pamela A., Clark, Jonathan, Wang, Lan-Zhen, Gilmour, Lesley, Squires, Matthew, Gilley, Rebecca, Foxton, Caroline, Newell, David R., Wedge, Stephen R., Cook, Simon J.
में प्रकाशित Cell Cycle (2016)

Inhibition of poly(ADP-ribose) polymerase-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft

द्वारा Senra, Joana M., Telfer, Brian A., Cherry, Kim E., McCrudden, Cian M., Hirst, David G., O’Connor, Mark J., Wedge, Stephen R., Stratford, Ian J.
प्रकाशित 2011

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy

द्वारा O'Neill, Daniel, Jones, Dominic, Wade, Mark, Grey, James, Nakjang, Sirintra, Guo, Wenrui, Cork, David, Davies, Barry R., Wedge, Steve R., Robson, Craig N., Gaughan, Luke
में प्रकाशित Oncotarget (2015)

Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System

द्वारा Hallett, Stephen T., Pastok, Martyna W., Morgan, R. Marc L., Wittner, Anita, Blundell, Katie L.I.M., Felletar, Ildiko, Wedge, Stephen R., Prodromou, Chrisostomos, Noble, Martin E.M., Pearl, Laurence H., Endicott, Jane A.
में प्रकाशित Cell Rep (2017)

O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma.

द्वारा Middleton, M. R., Lunn, J. M., Morris, C., Rustin, G., Wedge, S. R., Brampton, M. H., Lind, M. J., Lee, S. M., Newell, D. R., Bleehen, N. M., Newlands, E. S., Calvert, A. H., Margison, G. P., Thatcher, N.
प्रकाशित 1998

Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach

द्वारा Miller, Duncan C., Martin, Mathew P., Adhikari, Santosh, Brennan, Alfie, Endicott, Jane A., Golding, Bernard T., Hardcastle, Ian R., Heptinstall, Amy, Hobson, Stephen, Jennings, Claire, Molyneux, Lauren, Ng, Yvonne, Wedge, Stephen R., Noble, Martin E. M., Cano, Celine
में प्रकाशित Org Biomol Chem (2018)

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

द्वारा Noble, Richard A., Bell, Natalie, Blair, Helen, Sikka, Arti, Thomas, Huw, Phillips, Nicole, Nakjang, Sirintra, Miwa, Satomi, Crossland, Rachel, Rand, Vikki, Televantou, Despina, Long, Anna, Keun, Hector C., Bacon, Chris M., Bomken, Simon, Critchlow, Susan E., Wedge, Stephen R.
में प्रकाशित Haematologica (2017)

Guidelines for the welfare and use of animals in cancer research

द्वारा Workman, P, Aboagye, E O, Balkwill, F, Balmain, A, Bruder, G, Chaplin, D J, Double, J A, Everitt, J, Farningham, D A H, Glennie, M J, Kelland, L R, Robinson, V, Stratford, I J, Tozer, G M, Watson, S, Wedge, S R, Eccles, S A
प्रकाशित 2010