Circumventing Embryonic Lethality with Lcmt1 Deficiency: Generation of Hypomorphic Lcmt1 Mice with Reduced Protein Phosphatase 2A Methyltransferase Expression and Defects in Insuli...

по MacKay, Kennen B., Tu, Yiping, Young, Stephen G., Clarke, Steven G.
Опубликовано 2013

LMNA missense mutations causing familial partial lipodystrophy do not lead to an accumulation of prelamin A

по Tu, Yiping, Sánchez-Iglesias, Sofía, Araújo-Vilar, David, Fong, Loren G., Young, Stephen G.
Опубликовано в: Nucleus (2016)

Fibroblasts lacking nuclear lamins do not have nuclear blebs or protrusions but nevertheless have frequent nuclear membrane ruptures

по Chen, Natalie Y., Kim, Paul, Weston, Thomas A., Edillo, Lovelyn, Tu, Yiping, Fong, Loren G., Young, Stephen G.
Опубликовано в: Proc Natl Acad Sci U S A (2018)

Increased expression of LAP2β eliminates nuclear membrane ruptures in nuclear lamin–deficient neurons and fibroblasts

по Chen, Natalie Y., Kim, Paul H., Tu, Yiping, Yang, Ye, Heizer, Patrick J., Young, Stephen G., Fong, Loren G.
Опубликовано в: Proc Natl Acad Sci U S A (2021)

Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases

по Yang, Shao H., Chang, Sandy Y., Tu, Yiping, Lawson, Gregory W., Bergo, Martin O., Fong, Loren G., Young, Stephen G.
Опубликовано 2012

New Lmna knock-in mice provide a molecular mechanism for the ‘segmental aging’ in Hutchinson–Gilford progeria syndrome(†)

по Jung, Hea-Jin, Tu, Yiping, Yang, Shao H., Tatar, Angelica, Nobumori, Chika, Wu, Daniel, Young, Stephen G., Fong, Loren G.
Опубликовано 2014

Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency

по Coffinier, Catherine, Chang, Sandy Y., Nobumori, Chika, Tu, Yiping, Farber, Emily A., Toth, Julia I., Fong, Loren G., Young, Stephen G.
Опубликовано 2010

A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency

по Allan, Christopher M., Tran, Deanna, Tu, Yiping, Heizer, Patrick J., Young, Lorraine C., Fong, Loren G., Beigneux, Anne P., Young, Stephen G.
Опубликовано в: Exp Dermatol (2017)

An Absence of Nuclear Lamins in Keratinocytes Leads to Ichthyosis, Defective Epidermal Barrier Function, and Intrusion of Nuclear Membranes and Endoplasmic Reticulum into the Nucle...

по Jung, Hea-Jin, Tatar, Angelica, Tu, Yiping, Nobumori, Chika, Yang, Shao H., Goulbourne, Chris N., Herrmann, Harald, Fong, Loren G., Young, Stephen G.
Опубликовано в: Mol Cell Biol (2014)

An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair

по Yang, Shao H., Chang, Sandy Y., Yin, Liya, Tu, Yiping, Hu, Yan, Yoshinaga, Yuko, de Jong, Pieter J., Fong, Loren G., Young, Stephen G.
Опубликовано 2011

Targeted Disruption of the Idol Gene Alters Cellular Regulation of the Low-Density Lipoprotein Receptor by Sterols and Liver X Receptor Agonists

по Scotti, Elena, Hong, Cynthia, Yoshinaga, Yuko, Tu, Yiping, Hu, Yan, Zelcer, Noam, Boyadjian, Rima, de Jong, Pieter J., Young, Stephen G., Fong, Loren G., Tontonoz, Peter
Опубликовано 2011

An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria

по Davies, Brandon S.J., Barnes, Richard H., Tu, Yiping, Ren, Shuxun, Andres, Douglas A., Spielmann, H. Peter, Lammerding, Jan, Wang, Yibin, Young, Stephen G., Fong, Loren G.
Опубликовано 2010

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure

по Larsson, Mikael, Allan, Christopher M., Heizer, Patrick J., Tu, Yiping, Sandoval, Norma P., Jung, Rachel S., Walzem, Rosemary L., Beigneux, Anne P., Young, Stephen G., Fong, Loren G.
Опубликовано в: J Lipid Res (2018)

Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes

по Lee, Roger, Chang, Sandy Y., Trinh, Hung, Tu, Yiping, White, Andrew C., Davies, Brandon S.J., Bergo, Martin O., Fong, Loren G., Lowry, William E., Young, Stephen G.
Опубликовано 2010

Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2

по Lee, John M., Tu, Yiping, Tatar, Angelica, Wu, Daniel, Nobumori, Chika, Jung, Hea-Jin, Yoshinaga, Yuko, Coffinier, Catherine, de Jong, Pieter J., Fong, Loren G., Young, Stephen G.
Опубликовано 2014

Chylomicronemia Elicits Atherosclerosis in Mice

по Weinstein, Michael M., Yin, Liya, Tu, Yiping, Wang, Xuping, Wu, Xiaohui, Castellani, Lawrence W., Walzem, Rosemary L., Lusis, Aldons J., Fong, Loren G., Beigneux, Anne P., Young, Stephen G.
Опубликовано 2009

Modulation of LMNA splicing as a strategy to treat prelamin A diseases

по Lee, John M., Nobumori, Chika, Tu, Yiping, Choi, Catherine, Yang, Shao H., Jung, Hea-Jin, Vickers, Timothy A., Rigo, Frank, Bennett, C. Frank, Young, Stephen G., Fong, Loren G.
Опубликовано в: J Clin Invest (2016)

Palmoplantar keratoderma in Slurp1/Slurp2 double-knockout mice

по Allan, Christopher M., Heizer, Patrick J., Jung, Cris J., Tu, Yiping, Tran, Deanna, Young, Lorraine C., Fong, Loren G., de Jong, Pieter J., Beigneux, Anne P., Young, Stephen G.
Опубликовано в: J Dermatol Sci (2017)

NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes

по He, Cuiwen, Hu, Xuchen, Weston, Thomas A., Jung, Rachel S., Heizer, Patrick, Tu, Yiping, Ellison, Rochelle, Matsumoto, Ken, Gerhardt, Holger, Tontonoz, Peter, Fong, Loren G., Young, Stephen G., Jiang, Haibo
Опубликовано в: Biochem Biophys Res Commun (2018)

Cholesterol Intake Modulates Plasma Triglyceride Levels in GPIHBP1-deficient Mice

по Weinstein, Michael M., Tu, Yiping, Beigneux, Anne P., Davies, Brandon S. J., Gin, Peter, Voss, Constance, Walzem, Rosemary L., Reue, Karen, Tontonoz, Peter, Bensadoun, André, Fong, Loren G., Young, Stephen G.
Опубликовано 2010