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Fibroblasts lacking nuclear lamins do not have nuclear blebs or protrusions but nevertheless have frequent nuclear membrane ruptures

The nuclear lamina, an intermediate filament meshwork lining the inner nuclear membrane, is formed by the nuclear lamins (lamins A, C, B1, and B2). Defects or deficiencies in individual nuclear lamin proteins have been reported to elicit nuclear blebs (protrusions or outpouchings of the nuclear enve...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Chen, Natalie Y., Kim, Paul, Weston, Thomas A., Edillo, Lovelyn, Tu, Yiping, Fong, Loren G., Young, Stephen G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176609/
https://ncbi.nlm.nih.gov/pubmed/30224463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812622115
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