Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases

Protein farnesyltransferase (FTase) and protein geranylgeranyltransferase-I (GGTase-I) add 15- or 20-carbon lipids, respectively, to proteins that terminate with a CaaX motif. These posttranslational modifications of proteins with lipids promote protein interactions with membrane surfaces in cells,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yang, Shao H., Chang, Sandy Y., Tu, Yiping, Lawson, Gregory W., Bergo, Martin O., Fong, Loren G., Young, Stephen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2012
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243483/
https://ncbi.nlm.nih.gov/pubmed/22039581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021220
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky