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Reorganization of the nuclear architecture in the Drosophila melanogaster Lamin B mutant lacking the CaaX box

Lamins interact with the nuclear membrane and chromatin but the precise players and mechanisms of these interactions are unknown. Here, we tested whether the removal of the CaaX motif from Lamin B disrupts its attachment to the nuclear membrane and affects chromatin distribution. We used Drosophila...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Bondarenko, Semen M., Sharakhov, Igor V.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529411/
https://ncbi.nlm.nih.gov/pubmed/32960740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2020.1819704
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