LXR Regulates Cholesterol Uptake through Idol-dependent Ubiquitination of the LDL Receptor

par Zelcer, Noam, Hong, Cynthia, Boyadjian, Rima, Tontonoz, Peter
Publié 2009

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target

par Hong, Cynthia, Walczak, Robert, Dhamko, Helena, Bradley, Michelle N., Marathe, Chaitra, Boyadjian, Rima, Salazar, Jon V., Tontonoz, Peter
Publié 2011

Targeted Disruption of the Idol Gene Alters Cellular Regulation of the Low-Density Lipoprotein Receptor by Sterols and Liver X Receptor Agonists

par Scotti, Elena, Hong, Cynthia, Yoshinaga, Yuko, Tu, Yiping, Hu, Yan, Zelcer, Noam, Boyadjian, Rima, de Jong, Pieter J., Young, Stephen G., Fong, Loren G., Tontonoz, Peter
Publié 2011

TLE3 is a dual function transcriptional coregulator of adipogenesis

par Villanueva, Claudio J, Waki, Hironori, Godio, Cristina, Nielsen, Ronni, Chou, Wen-Ling, Vargas, Leo, Wroblewski, Kevin, Schmedt, Christian, Chao, Lily C., Boyadjian, Rima, Mandrup, Susanne, Hevener, Andrea, Saez, Enrique, Tontonoz, Peter
Publié 2011

The E3 Ubiquitin Ligase IDOL Induces the Degradation of the Low Density Lipoprotein Receptor Family Members VLDLR and ApoER2

par Hong, Cynthia, Duit, Sarah, Jalonen, Pilvi, Out, Ruud, Scheer, Lilith, Sorrentino, Vincenzo, Boyadjian, Rima, Rodenburg, Kees W., Foley, Edan, Korhonen, Laura, Lindholm, Dan, Nimpf, Johannes, van Berkel, Theo J. C., Tontonoz, Peter, Zelcer, Noam
Publié 2010

LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice

par Hong, Cynthia, Bradley, Michele N., Rong, Xin, Wang, Xuping, Wagner, Alan, Grijalva, Victor, Castellani, Lawrence W., Salazar, Jon, Realegeno, Susan, Boyadjian, Rima, Fogelman, Alan M., Van Lenten, Brian J., Reddy, Srinivasa T., Lusis, Aldons J., Tangirala, Rajendra K., Tontonoz, Peter
Publié 2012

The LXR–Idol axis differentially regulates plasma LDL levels in primates and mice

par Hong, Cynthia, Marshall, Stephanie M., McDaniel, Allison L., Graham, Mark, Layne, Joseph D., Cai, Lei, Scotti, Elena, Boyadjian, Rima, Kim, Jason, Chamberlain, Brian T., Tangirala, Rajendra K., Jung, Michael E., Fong, Loren, Lee, Richard, Young, Stephen G., Temel, Ryan E., Tontonoz, Peter
Publié dans Cell Metab (2014)

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization

par Chao, Lily C., Wroblewski, Kevin, Ilkayeva, Olga R., Stevens, Robert D., Bain, James, Meyer, Gretchen A., Schenk, Simon, Martinez, Leonel, Vergnes, Laurent, Narkar, Vihang A., Drew, Brian G., Hong, Cynthia, Boyadjian, Rima, Hevener, Andrea L., Evans, Ronald M., Reue, Karen, Spencer, Melissa J., Newgard, Christopher B., Tontonoz, Peter
Publié 2012