Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2

Lamins B1 and B2 (B-type lamins) have very similar sequences and are expressed ubiquitously. In addition, both Lmnb1- and Lmnb2-deficient mice die soon after birth with neuronal layering abnormalities in the cerebral cortex, a consequence of defective neuronal migration. The similarities in amino ac...

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Main Authors: Lee, John M., Tu, Yiping, Tatar, Angelica, Wu, Daniel, Nobumori, Chika, Jung, Hea-Jin, Yoshinaga, Yuko, Coffinier, Catherine, de Jong, Pieter J., Fong, Loren G., Young, Stephen G.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019497/
https://ncbi.nlm.nih.gov/pubmed/24672053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-01-0683
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