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Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2
Lamins B1 and B2 (B-type lamins) have very similar sequences and are expressed ubiquitously. In addition, both Lmnb1- and Lmnb2-deficient mice die soon after birth with neuronal layering abnormalities in the cerebral cortex, a consequence of defective neuronal migration. The similarities in amino ac...
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| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Cell Biology
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019497/ https://ncbi.nlm.nih.gov/pubmed/24672053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-01-0683 |
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