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Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency

Nuclear lamins are components of the nuclear lamina, a structural scaffolding for the cell nucleus. Defects in lamins A and C cause an array of human diseases, including muscular dystrophy, lipodystrophy, and progeria, but no diseases have been linked to the loss of lamins B1 or B2. To explore the f...

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Detalhes bibliográficos
Main Authors: Coffinier, Catherine, Chang, Sandy Y., Nobumori, Chika, Tu, Yiping, Farber, Emily A., Toth, Julia I., Fong, Loren G., Young, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841930/
https://ncbi.nlm.nih.gov/pubmed/20145110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908790107
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