Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration

Eitemau Tebyg

• Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2
  gan: Lee, John M., et al.
  Cyhoeddwyd: (2014)
• An Absence of Nuclear Lamins in Keratinocytes Leads to Ichthyosis, Defective Epidermal Barrier Function, and Intrusion of Nuclear Membranes and Endoplasmic Reticulum into the Nuclear Chromatin
  gan: Jung, Hea-Jin, et al.
  Cyhoeddwyd: (2014)
• Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons
  gan: Coffinier, Catherine, et al.
  Cyhoeddwyd: (2011)
• Mice that express farnesylated versions of prelamin A in neurons develop achalasia
  gan: Yang, Shao H., et al.
  Cyhoeddwyd: (2015)
• Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency
  gan: Coffinier, Catherine, et al.
  Cyhoeddwyd: (2010)