Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration

The role of protein farnesylation in lamin A biogenesis and the pathogenesis of progeria has been studied in considerable detail, but the importance of farnesylation for the B-type lamins, lamin B1 and lamin B2, has received little attention. Lamins B1 and B2 are expressed in nearly every cell type...

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Detalhes bibliográficos
Main Authors: Jung, Hea-Jin, Nobumori, Chika, Goulbourne, Chris N., Tu, Yiping, Lee, John M., Tatar, Angelica, Wu, Daniel, Yoshinaga, Yuko, de Jong, Pieter J., Coffinier, Catherine, Fong, Loren G., Young, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666708/
https://ncbi.nlm.nih.gov/pubmed/23650370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303916110
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