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Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration
The role of protein farnesylation in lamin A biogenesis and the pathogenesis of progeria has been studied in considerable detail, but the importance of farnesylation for the B-type lamins, lamin B1 and lamin B2, has received little attention. Lamins B1 and B2 are expressed in nearly every cell type...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666708/ https://ncbi.nlm.nih.gov/pubmed/23650370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303916110 |
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